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4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins

4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins

4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins

Part of the International Symposium on Frontiers in Molecular Science series
6–9 Sep 2022, Florence, Italy
Protein Chemistry, Proteins As Drug Target, Protein Structure and Function
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Thank you for your participation in ISFMS2022!

We would like to thank our chairs, committee members, speakers, and all the attendees for making such a great meeting!
You can already download you certificate by accessing your Sciforum account. Once you're logged-in, go to your profile and click on 'My certificates'.
For any question or comment, please send us an email to .
See you at the next edition!!

Welcome from the Chairs

Dear Colleagues,

We would like to invite you to The 4th ISFMS: Biochemistry, Molecular Biology and Druggability of Proteins, which will be held in the wonderful city of Florence, Italy, in the period September 6–9, 2022. The conference will be hosted at the University of Florence, in the biomedical campus nearby the main city hospital, which is easily accessible from the airport, train station or city center. Apart the high quality science which will be presented during the event, our fantastic location will afford the possibility to visit the city in which Leonardo da Vinci, Michelangelo and Galileo Galilei (to mention just a few personalities) lived and created some of their unique artistic and scientific masterpieces. The friendly and peaceful atmosphere of our city will surely favor nice scientific interactions and the possibility to establish interesting contacts with scientists from all over the world in a collaborative manner.

We look forward to seeing you in Florence.

Claudiu T. Supuran, Paola Gratteri, Silvia Selleri & Clemente Capasso

twitter logo Follow the conversation on Twitter with #ISFMS2022

Download the conference poster here.

Sponsored By

Media Partner

A special thanks to our collaborator Orto botanico - Antico giardino dei semplici

Conference Secretariat

Reyna Li
Ana Sanchis

Sponsoring Opportunities

For information regarding sponsorship and exhibition opportunities, please contact:
E-Mail:

Conference Chairs

Prof. Dr. Claudiu T. Supuran

University of Florence Neurofarba Department, Firenze, Italy

Prof. Dr. Paola Gratteri

University of Florence Neurofarba Department, Firenze, Italy

Prof. Dr. Silvia Selleri

University of Florence Neurofarba Department, Firenze, Italy

Dr. Clemente Capasso

National Research Council, Napoli, Italy

Conference Committee

Prof. Dr. Gyula Batta

University of Debrecen, Debrecen, Hungary

Introduction

Prof. Dr. Cheorl-Ho Kim

Department of Biological Sciences, College of Science, Sungkyunkwan University, Korea

Introduction

Prof. Dr. Maria Ruzzene

Department of Biomedical Sciences, University of Padova, Italy

Introduction

Prof. Dr. Barbara Jachimska

Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Poland

Introduction
Bio
www.researchgate.net/profile/Barbara_Jachimska

Prof. Dr. Carlos Salgueiro

NOVA School of Science and Technology, NOVA University Lisbon, Portugal

Introduction

Prof. Dr. Ryszard Lobinski

French National Center for Scientific Research (CNRS), France

Introduction

Prof. Dr. Tiziana Marino

Dipartimento di Chimica e Tecnologie Chimiche, Presidente SCI Sezione Calabria, Italy

Introduction

Dr. Anindita Das

Division of Cardiology, Pauley Heart Center, Department of Internal Medicine, Virginia Commonwealth University, USA

Introduction

Prof. Dr. Nikolai Barlev

Institute of Cytology of Russian Academy of sciences, Russia

Introduction

Local Organizers

Local Organizing Committee

Dr. Alessandro Bonardi
Dr. Alessio Nocentini
Dr. Andrea Angeli
Andrea Ammara
Simone Giovannuzzi
Francesco Mori
Irene Fallai

Coordinators of the Local Organizing Committee

Prof. Paola Gratteri and Prof. Claudiu T. Supuran

Keynote Speakers

Prof. Dr. Shoukat Dedhar

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada

Introduction
Talk
Hypoxia and Ferroptosis: Co-targeting Approaches in Cancer
Bio
Dr Shoukat Dedhar is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver. He is a Fellow of the Royal Society of Canada. Known for his seminal discovery of Integrin-Linked Kinase (ILK), an essential protein involved in the regulation of cytoskeletal organization and signal transduction, he has also made significant contributions in the field of tumour microenvironment/hypoxia, and co-developed a new inhibitor of CAIX, currently in clinical trials.

Prof. Dr. Binghe Wang

Department of Chemistry, and Center for Diagnostics and Therapeutic, Georgia State University, Atlanta, GA, USA

Introduction
Bio
Dr. Binghe Wang is Regents’ Professor of Chemistry, Georgia Research Alliance Eminent Scholar in Drug Discovery, and Director of Center for Diagnostics and Therapeutics at Georgia State University. Dr. Wang obtained his B.S. degree in medicinal chemistry from Beijing Medical College in 1982, and his Ph.D. degree in medicinal chemistry from the University of Kansas in 1991. He served at the University of Oklahoma and at North Carolina State University before he was recruited to a Georgia Research Alliance Eminent Scholar position at Georgia State University, where he also served as Chair of the Department of Chemistry, Associate Dean for Natural and Computational Sciences, Associate Dean for Research, Graduate Studies, and Innovation, and Interim Dean of the College of Arts and Sciences. Dr. Wang’s research covers drug design, drug delivery, chemosensing, chemical biology, and organic chemistry. He has published over 320 scientific papers and given over 220 invited lectures worldwide. He served for 20 years as the Editor-in-Chief of a high-impact journal, Medicinal Research Reviews between 2000-2019, and founding serial editor of “Wiley Series in Drug Discovery and Development,” which has published over 20 volumes. He has edited books in areas including drug design, drug delivery, pharmaceutical profiling, chemosensing, carbohydrate recognition, and therapeutic applications of carbon monoxide. Internationally, Dr. Wang has served on many panels and editorial boards including his 7-year membership on the Synthetic and Biological Chemistry-A Study Section (SBC-A) at the NIH. He has also led or participated in the organization, and/or presided over more than 40 international symposia and conferences.

Prof. Dr. Marianna A. Patrauchan

Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA

Introduction
Talk
Molecular pillars of calcium signaling in a bacterial pathogen, Pseudomonas aeruginosa.
Bio
Dr. Patrauchan is a Professor of Microbiology in the Department of Microbiology and Molecular Genetics at Oklahoma State University. She holds a PhD in Microbiology (National Academy of Sciences, Ukraine) and received postdoctoral training in molecular microbiology (Michigan State University, Montana State University, and University of British Columbia). Dr. Patrauchan’s research focuses on understanding calcium signaling in a human pathogen Pseudomonas aeruginosa.

Prof. Dr. William Donald

School of Chemistry, University of New South Wales (UNSW) Australia, Sydney, Australia

Introduction
Talk
Multiplexed screening of thousands of natural products for protein-ligand binding in native mass spectrometry
Bio
William A. Donald is an Associate Professor, Australian Research Council Future Fellow, and Scientia Fellow in the School of Chemistry at the University of New South Wales, Sydney. He received his B.Sc. degree in Chemistry from Seattle University in 2005 and a Ph.D. from the University of California, Berkeley in 2010. After a research fellowship at the University of Melbourne, he joined the School of Chemistry at the University of New South Wales in 2013. He is currently an associate editor for the Journal of Enzyme Inhibition and Medicinal Chemistry. His research interests include mass spectrometry and ion chemistry, with an emphasis on developing and applying instrumentation and methods to problems of interest in biochemistry.

Prof. Dr. Jean-Yves WINUM

IBMM - Pôle Chimie Balard Recherche, University of Montpellier, Montpellier, France

Introduction
Talk
Innovative approaches targeting carbonic anhydrases: an update.
Bio
Jean-Yves Winum received his PhD in chemistry from the University of Montpellier (France) in 1998. He then worked as a postdoctoral fellow in the Chemistry department of Georgetown University (Washington, DC) and of the University of Geneva (Switzerland). In 1999, he joined the University of Montpellier, where he is now Full Professor. His research interests are focused on organic/medicinal chemistry of metalloenzyme inhibitors. He published more than 190 articles (h-index 44) in this field.

Prof. Dr. Ionel Mangalagiu

Faculty of Chemistry, “Alexandru Ioan Cuza” University of Iasi, Iasi, Romania

Introduction
Talk
Dual- or Multi- Trageting Azaheterocycles: Next Generation of Drugs in Medicinal Chemistry.
Bio
Dr. Mangalagiu is a professor of organic and medicinal chemistry and Vice-Rector with research at “Alexandru Ioan Cuza” University of Iasi, Romania. He has nearly 30 years of experience in the research, focused in the area of Heterocycles Compounds. He has over 200 papers, 15 patents, 3 international chapter books, etc. He was Visiting Professor and/or invited speaker to prestigious foreign universities (Ludwig Maximilianus University Munchen, Technische Universität Braunschweig, University of Florence, Universite D’Angers), awarded with numerous prizes and honours: DAAD and NATO award, “Costin D. Nenitescu Medal” (Romanian Society of Chemistry), “Al.I.Cuza University Award in Research”, Special Award of Croatian Association of Inventors, etc. More information’s to: http://teclu.chem.uaic.ro/mangalagiu; ORCID number 0000-0002-4632-5076

Prof. Dr. Vladimir N. Uversky

Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, USA

Prof. Dr. Giuseppina De Simone

Biostructure and Bioimaging Institute-CNR, Naples, Italy"

Introduction
Bio
Giuseppina De Simone graduated in chemistry at the University of Naples Federico II (1993). She worked from August 1994 to January 1995 at the Drug Design Group-Sandoz Pharma AG in Basel, and from September 1995 to February 1996 at the University of Pavia. From November 1996 to January 1997, she was visiting scientist at the Max Plank Institute-Hamburg Germany. In 1998 she received her PhD at the University of Naples. Since 2010, she is Research Director at the Institute of Biostructures and Bioimaging of the Italian National Research Council. Her research activities are focused on the biochemical and structural characterization of enzymes involved in human diseases. She published more than 160 articles (Google scholar h-index 49) in this field.

Prof. Dr. Daniel P. Flaherty

Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, USA

Introduction
Talk
Bacterial carbonic anhydrase inhibitors for the treatment of drug resistant bacteria: A classical drug scaffold gets a new purpose
Bio
Dr. Flaherty received his Ph.D. in pharmaceutical sciences at the University of Nebraska Medical Center. He then moved to the University of Kansas and joined an NIH sponsored medicinal chemistry lab under the direction of Dr. Jeffrey Aubé as a post-doctoral researcher and later as a research track faculty. He is now an assistant professor of medicinal chemistry in the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University focused on drug design for new antibiotics.

Dr. Łukasz Jaremko

Molecular Diagnostics and Drug Discovery (MD3) Group, Smart-Health Initiative (SHI), Red Sea Research Center (RSRC), Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Kingdom of Saudi Arabia

Introduction
Talk
Elevated protein dynamics and druggability
Bio
Research in Professor Łukasz Jaremko's Molecular Diagnostics and Drug Discovery (MD3) group focuses on atomic-level insight into essential and topical questions from biochemistry and medicine, such as, e.g., the primary molecular bases of cancer, including leukaemia and lung cancer (Nature, 2021). The team is actively working in the field of targeted drug design and discovery, using structure-dynamics analysis to search for small molecules (ligands) that interact specifically with the disease-associated proteins. Identified lead compounds are then engineered to increase their binding and, thus therapeutic potency against cancer (Nature Chem Biol, 2021). Biomolecular nuclear magnetic resonance (NMR) spectroscopy is the crucial experimental technique used and refined (J Chem Phys B, 2015; Angewandte Chem, 2016; J Biomol NMR, 2018, 2020) to tackle challenging macromolecular assemblies (Nature Chem Biol, 2013, 2021; Science, 2014; Nature Communications, 2016, 2017; Nucleic Acids Res, 2019; Am J Hum Genetics, 2019; Chemical Science, 2020; eLife, 2021; Nature 2021; Mol. Cell 2021). These NMR-based structural studies are then combined with molecular and enzymatic assays as well as other state-of-the-art biophysical techniques such as X-ray crystallography, electron microscopy, circular dichroism and molecular dynamics simulations to get further insights into the complex biological systems essential for human health. Professor Łukasz Jaremko has published over 90 peer-reviewed papers in international journals covering original research of both methods development and application to address and monitor the pivotal biological, biomedical and environmental phenomena.

Registration

The registration fee includes attendance to all conference sessions, welcome cocktail, and morning/afternoon coffee breaks.

Participation to the conference is considered final only once the registration fees have been paid. The number of participants is limited: once the number of paid registrations reaches the maximum number of participants, unpaid registrations will be cancelled.

Please note that, in order to finalize the scientific program in due time, at least one registration by anyone of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 20 July 2022. Your abstract will be withdrawn if your registration is not complete by this date.

Authors with multiple contributions: Please note that one author registration will cover only ONE accepted contribution. Authors presenting more than 1 contribution during the event will be charged 25 euro per additional abstract (e.g., 1 author with 2 abstracts: registration fee + 25 euro; 2 authors with 3 abstracts: 2 registration fees + 25 euro; etc.)

Authors and reviewers of IJMS: Please note that the authors and reviewers of IJMS from the last 5 years will receive a 15% discount on the registration fees. This discount is not immediate, so you need to add the code AUT/REV-ISFMS2022 during your registration process. For any question or doubt, please send us an email to .

Certificate of Attendance: After the event, the participants of ISFMS2022 will be able to download an electronic Certificate of Attendance by log-in at their Sciforum personal account. Once you're logged-in, go to your profile and click on 'My certificates'. A list of all Sciforum events you've attended is available and you simply have to click on "Download" next to the correct event.

Conference Dinner: A Social Dinner will be served on Thursday, 8 September at 20.30h (further information below). Please note that the conference fee does not include this social event. Therefore, if you plan to attend the dinner, please make sure you select this extra when registering to the conference (Price per person: 50 euro). Anyone wishing to attend the conference social dinner should register and pay at this website before 31 August.

Registration Options
Early Bird
Until 20th July 2022 		Regular
Until 10th August 2022 		Late
From 11th August 2022 		Supported documents
Student 250.00 EUR 350.00 EUR 450.00 EUR Scanned copy or photograph of your current student ID is required.
Editorial Board Members/Guest Editors of IJMS 350.00 EUR 450.00 EUR 550.00 EUR
Post-Docs, PIs & Senior Scientists 450.00 EUR 550.00 EUR 650.00 EUR
Commercial 700.00 EUR 800.00 EUR 900.00 EUR
Registration Options
Price
Social Dinner Registration 50.00 EUR

Free Registration Options
Waived Fees: Invited Speakers and MDPI Guests

Cancellation policy

Cancellation of paid registration is possible under the terms listed below:

> 2 months before the conference

Full refund but 60 EUR are retained for administration

> 1 month before the conference

Refund 50% of the applying fees

> 2 weeks before the conference

Refund 25% of the applying fees

< 2 weeks before the conference

No refund

Disclaimer
In the unlikely event that MDPI shall deem it necessary to cancel the conference, all pre-paid registration fees will be reimbursed. MDPI shall not be liable for reimbursing the cost of travel or accommodation arrangements made by individual delegates.

Photographs and/or video will be taken during the conference
By taking part in this event you grant the event organizers full rights to use the images resulting from the photography/video filming, and any reproductions or adaptations of the images for fundraising, publicity or other purposes to help achieve the conference’s aims. This might include (but is not limited to), the right to use them in their printed and online publicity, social media, press releases and funding applications.

Payment methods

Wire transfer, Credit card

Instructions for Authors

Instructions

The "4th ISFMS — Biochemistry, Molecular Biology and Druggability of Proteins" will accept abstracts only.

The accepted abstracts will be available online on Sciforum.net during and after the conference. Moreover, participants will have the opportunity to contribute with a full manuscript to the special issue "Biochemistry, Molecular Biology and Druggability of Proteins" in the journal IJMS.

To present your research at the event

  • Create an account on Sciforum if you do not have one, then click on ‘New Submission’ on the upper-right corner of the window, or by clicking on ‘Submit Abstract’ at the top of this webpage.
  • Indicate what thematic area is best suited for your research.
  • Submit an abstract in English - the word limits are: minimum 150 words and maximum 300 words.
  • The deadline to submit your abstract is 24 June 2022. You will be notified by 15 July 2022 about the acceptance for poster presentation.
  • Upon submission, you can select if you wish to also be considered for oral presentation. Following assessment by the Chairs, you will be notified by 15 July 2022 in a separate email whether your contribution has been accepted for oral presentation.
  • Please note that, in order to finalize the scientific program in due time, at least one registration by any of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 2 August 2022. Your abstract will be withdrawn if your registration is not complete by this date.

Oral Presentations

Short talks will be 15 min long including questions (12+3 Q&A). The typical presentation should be up to 10–12-minute talk.
All presentations must be uploaded in advance. Please bring your presentation to the registration desk at least 30 min before the start of your session, or at the end of the previous day for the early morning sessions. A technician will be available to assist you.

Poster Information

Maximum poster size limited to 90 × 140cm, vertical orientation preferred. Please print your poster prior to the conference.
A plan of the poster session will be circulated later on.

Publication Opportunities

  • All accepted abstracts will be available online in Open Access form on Sciforum.net.
  • Participants of this conference are cordially invited to contribute with a full manuscript to our Special Issue "Biochemistry, Molecular Biology and Druggability of Proteins" in the journal IJMS.
  • The submission deadline for this special issue is 28 February 2023. Conference participants will be granted a 15% discount on the publication fees. Please note that no other institutional discounts will be applicable, except from reviewers’ discount vouchers.
  • IJMS is indexed by the Science Citation Index Expanded (Web of Science), MEDLINE (PubMed), and other databases, and has an Impact Factor of 5.923 (2020).

Venues for ISFMS2022

The 4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins conference will take place in two different locations:

1. Tuesday 06 September 2022, for the opening ceremony, 1st session and Welcome cockatil it will be celebrated on Rectorate of University of Florence, Piazza San Marco 4 50121 Florence


Google maps address: Rectorate of University of Florence, Piazza San Marco 4 50121 Florence


2. All the other days the conference will take place at Centro Didattico Morgagni (CDM) - Morgagni Didactic Center at Via Gian Battista Morgagni 40, 50134 Florence

Google maps address: Centro Didattico Morgagni (CDM) - Morgagni Didactic Center at Via Gian Battista Morgagni 40, 50134 Florence

How to get to the CDM:

The tramway line is by far the best option. Centro Didattico Morgagni is served by the T1 tram line. From Santa Maria Novella train station you can take the T1 line towards “Careggi-Ospedale” and stop at “Morgagni Università” (frequency every 5 to 10 mins). The ride from the train station to the conference building takes about 20 minutes. It is possible to buy tickets at every stop, using cash or contactless credit cards. Tickets must then be validated on board. For information on this line and other routes you can directly consult the website www.gestramvia.it.

Social Dinner

The Conference Social Dinner will take place on 8 September at 20:30h at Ristorante Il Bargello.

Please note that the conference fee does not include this social event. The price per person to attend the Social Dinner is 50 euro. Anyone wishing to attend the conference social dinner should register and pay at this website before 31 August.

Address: Piazza della Signoria 4/red 50122 Firenze FL

Conference Program

Tuesday 06 September 2022

Rectorate of University of Florence, Piazza San Marco 4 50121 Florence

14:30 - 15:30

Registration check

15:30 - 15:45

Greetings from Prof. Debora Berti, Prorector for research, University of Florence

15:45 - 16:00

Welcome and chairing from Prof. Claudiu T. Supuran, chair of the conference

16:00 - 17:00

Keynote talk: Shoukat Dedhar, University of British Columbia, Canada
Targeting the Tumour Microenvironment

17:15 - 19:00

Welcome cocktail

Wednesday 07 September 2022

Centro Didattico Morgagni (CDM) - Morgagni Didactic Center
Via G.B. Morgagni 40, 50134 Florence
Session chaired by Dr. Clemente Capasso

09.00-10.00

Keynote talk: W. Alexander Donald, University of New South Wales, Australia
Multiplexed screening of thousands of natural products for protein binding in native mass spectrometry

10.00-10.30

Daniel Lietha - Structure and force activation of adhesion signalling

10:30 – 11:00 Coffee break

Session chaired by Dr. Clemente Capasso

11.00-11.30

Catherine Michaux - Revealing intrinsic disorder and aggregation properties of the DPF3 zinc finger proteins

11.30-12.00

Felix Nagel - Biophysical and Structural Insights into a Pancreatitis Associated Kazal Inhibitor

12.00-12.30

Mietha Van der Walt - Application of reverse pharmacophore mapping to search for protein targets of istradefylline – a drug repurposing perspective

12.30-13.00

Spyridon Gourdoupis - FEN1 as a target for confining oncogenesis

13.00-13.30

Filippo Favretto - Functional and Structural Characterization of two Cyclophilins from the parasite Toxoplasma gondii

13:30 – 15:00 Lunch time
Session chaired by Prof. Dr. Paola Gratteri and Prof. Dr. Claudiu T. Supuran

15.00-16.00

Keynote talk: Giuseppina De Simone, CNR Naples, Italy
Biochemical and structural studies on human carbonic anhydrase IX: a promising therapeutic target for cancer treatment

16.00-16.30

Anne Susemihl - BCL11B CCHC Zinc Finger Domain and Its Potential for Cancer Therapy

16.30-17.00

Aida Serra - Industry by-product EVs (BP-EVs) as a novel compound delivery platform for protein target within the Central Nervous System

17:00 – 17:30 Coffee break

17.30-18.00

Elena Krachmarova - Effect of SARS-CoV-2 ORF6 protein on DNA replication in eukaryotic cells

18.00-18.45

POSTER Session 1

Thursday 08 September 2022

Centro Didattico Morgagni (CDM) - Morgagni Didactic Center
Via G.B. Morgagni 40, 50134 Florence
Session chaired by Prof. Dr. Silvia Selleri and Dr. Clemente Capasso

09.00-10.00

Keynote talk: Binghe Wang, Georgia State University, USA
Examining the Therapeutic Effects of Carbon Monoxide: Seeing both the Forest and the Trees in Understanding Its Hemoprotein Targets

10.00-10.30

Jiri Cerven - Targetting Topoisomerase IIa: back to the drawing board via Z-DNA

10:30 – 11:00 Coffee break

11.00-12.00

Keynote talk: Marianna Patrauchan, Oklahoma State Univ., USA
Molecular pillars of calcium signaling in a bacterial pathogen: Pseudomonas aeruginosa.

12.00-12.30

Patrycja Gralewska - ATRi and CHK1i significantly increased chromosomal abnormalities caused by olaparib in HGSOC BRCAMUT and BRCAWT ovarian cancer cell lines

12.30-13.00

Katarzyna Walczewska-Szewc - How can interaction with prolyl oligopeptidase possibly trigger α-synuclein aggregation?

13.00-13.30

Marco Pedretti - Functional characterization of cystathionine gamma lyase from Pseudomonas aeruginosa

13:30 – 15:00 Lunch time
Session chaired by Prof. Dr. Giuseppina De Simone

15.00-16.00

Keynote talk: Jean-Yves Winum, University of Montpellier, France
Innovative approaches targeting carbonic anhydrases: an update

16.00-16.30

Gyula Batta - DMSO Induced Unfolding of the Antifungal Disulfide Protein PAF: a combined NMR and DSC study

16.30-17.00

Leandar Litov - Human interferon gamma is a potential inhibitor of SARS-Cov-2 Orf6 activity

17:00 – 17:30 Coffee break
Session chaired by Prof. Dr. Giuseppina De Simone

17.30-18.00

Massimiliano Gasparrini - Human extracellular NAMPT and NAPRT mediate inflammatory response through TLR4-binding: molecular insights into the mechanism of interaction

18.00-18.45

POSTER Session 2

20:30

Social Dinner

Friday 09 September 2022

Centro Didattico Morgagni (CDM) - Morgagni Didactic Center
Via G.B. Morgagni 40, 50134 Florence
Session chaired by Prof. Dr. Jean-Yves WINUM

09.00-10.00

Keynote talk: Daniel P. Flaherty, Purdue University, USA
Bacterial carbonic anhydrase inhibitors for the treatment of drug resistant bacteria: A classical drug scaffold gets a new purpose.

10.00-10.15

Arianna Giacomini- Inhibition of Carbonic Anhydrase IX induces mitochondrial oxidative stress and apoptosis in multiple myeloma

10.15-10.45

Carsten Zeilinger - Strategies to display susceptibility of targets for compounds

10:45 – 11:15 Coffee break
Session chaired by Prof. Dr. Jean-Yves WINUM

11.15-12.15

Keynote talk: Lukasz Jaremko, King Abdullah University of Science and Technology, Saudi Arabia
Biological motions, gene regulation and drugs

12.15-12.45

Barbara Jachimska - Fibrinogen corona on the dendrimer nanoparticles

12.45-13.15

Olga Alekseeva - Variation in viral tropism belongs to IDPR positions in structural proteins of enterovirus

13:15 – 14:45 Lunch time
Session chaired by Prof. Dr. Claudiu T. Supuran, Prof. Dr. Paola Gratteri, Prof. Dr. Silvia Selleri and Dr. Clemente Capasso

14.45-15.45

Keynote talk: Vladimir Uversky, Univresity of South Florida, USA
Protein structure-function continuum: On the roles of intrinsic disorder in protein functionality

15.45-16.15 Ceremony awards and closing of the conference

Poster sessions

Posters have been divided in two groups and each poster will be presented in one of the two poster sessions:

  • Poster Session 1 – Wednesday 07 September 2022; 18.00-18.45h
  • Poster Session 2 – Thursday 08 September 2022; 18.00-18.45h

The session in which each poster will be presented can be found HERE, together with the posters' numbers, titles, and presenters' names. Please contact us if the poster presenter's name is incorrect in the list.

Please print your poster prior to the conference. Note that maximum poster size is limited to 90x140cm, vertical orientation preferred.

Venue, Travel and Accommodation

Florence

Florence is a city in central Italy and the capital of the Tuscany region. During the Middle Ages, Florence was a centre of European trade and finance, and one of the wealthiest cities of that era.

The city attracts millions of tourists each year, and UNESCO declared the Historic Center of Florence a World Heritage Site in 1982. The city is noted for its culture, Renaissance art and architecture and monuments. The city also boasts numerous museums and art galleries, such as the Uffizi Gallery and the Palazzo Pitti, and still influences the fields of art, culture and politics to this day. Due to Florence's artistic and architectural heritage, Forbes has ranked it as one of the most beautiful cities in the world.

For more information visit http://www.firenzeturismo.it/en/.

Venue

The conference will take place in the biomedical campus of University of Florence, Viale G. Morgagni.


Best way to travel here

Florence may be reached directly by plane. The airport has connections with many of the main transport hubs in Europe (Rome, Milan, Paris, Frankfurt, Munich, Zurich) and a tram service connects the airport to the city centre. By train, it is a 90-minute trip from Rome or Milan where the largest airports in Italy are located. Pisa airport is just one hour from Florence by train and there are many flights into this city too.

The biomedical campus is 15 min by tram (T1) from the main train station which is in the city centre. Florence is a relatively small city (around 300 000 residents) and the public transportation (trams, trains, buses) is efficient and inexpensive.

Accommodation

There are huge numbers of tourists visiting Florence and Tuscany each year, in every season. For this reason, the accommodation should be booked in advance. There is a large number of hotels, B&Bs, Airbnbs or apartments which can be booked online by using booking.com or similar services. The best location to choose would be around the Santa Maria Novella train station or city centre, where the journey to the conference site will take roughly 15 minutes.

Beware of Unauthorized Registration and Hotel Solicitations
Note that Sciforum is the only official registration platform to register to ISFMS2022, and that we are not associated with any hotel agency. While other hotel resellers and travel agencies may contact you with offers for your trip, they are not endorsed by or affiliated with ISFMS2022 or Sciforum. Beware that entering into financial agreements with non-endorsed companies can have costly consequences.

Event Awards

The Sponsor, IJMS, offers two Best Posters Awards and one Best Oral Presentation award to our conference participants, which will be announced during the Award Ceremony on the last day of the conference.

The Awards
Best Poster Award (300€)

Number of Awards Available: 2

The two Best Posters will be selected by all conference attendees through secret vote.
Best Oral Presentation Award (500€)

Number of Awards Available: 1

The Best Oral Presentation will be selected by the Scientific Committee after evaluation of all selected talks presented during the conference

Sponsors and Partners

Sponsors and Partners


Sponsoring opportunities
If you are interested in knowing the sponsorship options for ISFMS2022 please look at our Sponsorship form.

For sponsorship and exhibition opportunities, please do not hesitate to contact us for more information.

Organizers


Sponsors


Media Partners

Conference Book

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Coronavirus, advice from the University of Florence

ENTERING ITALY

Italy applies health-related restriction measures to incoming travellers, which may vary depending on their country of origin. You can find actualized information on the following website: https://www.italia.it/en/useful-info/covid-19-updates

USE OF MASKS IN UNIVERSITY OF FLORENCE

Masks should be worn in the venue facilities during the talks and when moving across common areas. You may take them off during the coffee or lunch breaks, and when going outside the building. Thank you for your collaboration!

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